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Guideline · 2026-05-28

NICE expands tirzepatide weight-management eligibility in England (TA1026 update)

National Institute for Health and Care Excellence (NICE) revised TA1026 May 2026, lowering the BMI threshold to ≥30 (from ≥35) for NHS-funded tirzepatide. ~250,000 additional UK adults newly eligible.

NICE updated technology appraisal TA1026 on May 27, 2026, expanding NHS-funded tirzepatide eligibility for chronic weight management. The BMI threshold dropped from ≥35 to ≥30 (or ≥27.5 in adults of South Asian, Chinese, Other Asian, Middle Eastern, Black African, or African-Caribbean family origin per ethnicity-adjusted criteria).

Practical impact for UK patients: an estimated 250,000 additional adults are now NHS-eligible, joining the ~150,000 currently treated. The 24-month treatment cap + 5% loss-at-6-months stopping rule remain in place.

For US readers: NICE guidance often signals where US payer-coverage moves 12-18 months later. The ethnicity-adjusted BMI cutoffs (−2.5 kg/m² for South Asian, Chinese, Other Asian, Middle Eastern, Black African, African-Caribbean) are increasingly adopted in commercial PA policies.

We've added the NICE ethnicity-adjusted BMI cutoffs to our /tools/glp1-eligibility-checker. See also /best-glp1-for/postmenopausal for the Mayo Jan-2026 HRT-synergy data which factored into the TA1026 cost-effectiveness analysis.

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