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Drug information

GLP-1 Medications

Compare the major GLP-1 medications side by side. All data sourced from FDA prescribing information.

  • FDA-sourced
  • Peer-reviewed
  • Updated weekly

Most searched

  • Wegovy (semaglutide) — GLP-1 receptor agonist medication

    GLP-1 receptor agonist

    Wegovy

    semaglutide

    Avg cost: $1349.02/mo

    See overview
  • Zepbound (tirzepatide) — GIP/GLP-1 dual receptor agonist medication

    GIP/GLP-1 dual receptor agonist

    Zepbound

    tirzepatide

    Avg cost: $1059.87/mo

    See overview
  • Ozempic (semaglutide) — GLP-1 receptor agonist medication

    GLP-1 receptor agonist

    Ozempic

    semaglutide

    Avg cost: $935.77/mo

    See overview

Pivotal-trial weight loss compared

Mean total-body-weight reduction reported by each medication’s pivotal Phase 3 trial. Different trial populations, durations, and dosing make exact head-to-head comparison imperfect — but the magnitude differences are real.

0%5%10%15%20%25%ZepboundSURMOUNT-1, 72 wk−22.5%WegovySTEP-1, 68 wk−14.9%FoundayoATTAIN-1, 72 wk−12.4%SaxendaSCALE, 56 wk−8.0%
Mean weight loss reported in each medication’s pivotal Phase 3 trial.

Active ingredients sourced from 4 editorial entries; see /ingredients for per-molecule breakdowns.

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GLP-1 receptor agonist (daily injection)

Saxenda

Generic: liraglutide

Novo Nordisk

~$1349.00/mo

View details

GLP-1 receptor agonist

Ozempic

Generic: semaglutide

Novo Nordisk

~$997.58/mo

View details

GLP-1 receptor agonist

Wegovy

Generic: semaglutide

Novo Nordisk

~$1349.02/mo

View details

GLP-1 receptor agonist

Ozempic

Generic: semaglutide

Novo Nordisk

~$935.77/mo

View details

GLP-1 receptor agonist (oral tablet)

Rybelsus

Generic: semaglutide (oral)

Novo Nordisk

~$1029.00/mo

View details

GIP/GLP-1 dual receptor agonist

Zepbound

Generic: tirzepatide

Eli Lilly

~$1059.87/mo

View details

GIP/GLP-1 dual receptor agonist

Mounjaro

Generic: tirzepatide

Eli Lilly

~$1023.04/mo

View details