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glpverdict
Editorial medical reviewFDA & peer-reviewed sourcesUpdated weeklyMedically reviewed content
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Drug information

GLP-1 Medications

Compare the major GLP-1 medications side by side. All data sourced from FDA prescribing information.

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  • Peer-reviewed
  • Updated weekly

Side-by-side comparison

Compare two GLP-1 medications

Pick any two — we render head-to-head efficacy, cost, side effects, and dosing.

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Pivotal-trial weight loss compared

Mean total-body-weight reduction reported by each medication’s pivotal Phase 3 trial. Different trial populations, durations, and dosing make exact head-to-head comparison imperfect — but the magnitude differences are real.

0%5%10%15%20%25%ZepboundSURMOUNT-1, 72 wk20.9%WegovySTEP-1, 68 wk14.9%FoundayoATTAIN-1, 72 wk12.4%SaxendaSCALE, 56 wk8.0%
Mean weight loss reported in each medication’s pivotal Phase 3 trial.

Active ingredients sourced from 4 editorial entries; see /ingredients for per-molecule breakdowns.

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