Drug information
Compare the major GLP-1 medications side by side. All data sourced from FDA prescribing information.
Mean total-body-weight reduction reported by each medication’s pivotal Phase 3 trial. Different trial populations, durations, and dosing make exact head-to-head comparison imperfect — but the magnitude differences are real.
Active ingredients sourced from 4 editorial entries; see /ingredients for per-molecule breakdowns.
GLP-1 receptor agonist (daily injection)
Generic: liraglutide
Novo Nordisk
~$1349.00/mo
GLP-1 receptor agonist
Generic: semaglutide
Novo Nordisk
~$997.58/mo
GLP-1 receptor agonist
Generic: semaglutide
Novo Nordisk
~$1349.02/mo
GLP-1 receptor agonist
Generic: semaglutide
Novo Nordisk
~$935.77/mo
GLP-1 receptor agonist (oral tablet)
Generic: semaglutide (oral)
Novo Nordisk
~$1029.00/mo
GIP/GLP-1 dual receptor agonist
Generic: tirzepatide
Eli Lilly
~$1059.87/mo
GIP/GLP-1 dual receptor agonist
Generic: tirzepatide
Eli Lilly
~$1023.04/mo