HomeResearch Β· GLP-1 cash price spread 2026

Original-data investigation Β· June 2026

The 2026 GLP-1 cash price spread: 25 providers compared

We pulled cash-pay prices from 25 telehealth providers, compounding pharmacies, manufacturer-direct programs, and pharmacy-coupon platforms. The 2026 floor is $149/mo. The ceiling is $1,349/mo. Same active molecules. Here is the full table with source links.

The full table

Sorted by category, then by starting monthly cash price. Source link on every row.

ProviderCategoryDrugStarting/moMaintenance/moSource
Henry MedsCompounded 503ACompounded semaglutide$297$297Source
Mochi HealthCompounded 503ACompounded semaglutide$269$269Source
EdenCompounded 503ACompounded semaglutide$296$296Source
FuturHealthCompounded 503ACompounded semaglutide$229$229Source
Henry Meds (tirzepatide)Compounded 503ACompounded tirzepatide$449$449Intake screen
Mochi Health (tirzepatide)Compounded 503ACompounded tirzepatide$459$459Intake screen
Push HealthCompounded 503ACompounded semaglutide$199$199Intake screen
Sesame CareCompounded 503ACompounded semaglutide$249$249Intake screen
Hims (oral Wegovy)Lowest brand-name cash priceBrand-name telehealthOral Wegovy 25mg$149$199Source
Hims (Wegovy injection)Brand-name telehealthWegovy 2.4mg$499$499Intake screen
Ro (Wegovy)Brand-name telehealthWegovy 2.4mg$999$1349Source
Ro (Zepbound)Brand-name telehealthZepbound 15mg$999$1086Intake screen
Sequence (Wegovy)Brand-name telehealthWegovy 2.4mg$1349$1349Intake screen
Found (Wegovy)Brand-name telehealthWegovy 2.4mg$1100$1349Intake screen
Calibrate (Wegovy)Bundled with 12-month coachingBrand-name telehealthWegovy 2.4mg$1249$1349Intake screen
Form Health (Wegovy)Brand-name telehealthWegovy 2.4mg$1199$1349Intake screen
PlushCare (Wegovy)Brand-name telehealthWegovy 2.4mg$1075$1349Intake screen
MEDvi (Mounjaro)Brand-name telehealthMounjaro 15mg$1029$1187Intake screen
Lilly Direct (Zepbound vial 2.5mg)Manufacturer directZepbound vial$349$349Source
Lilly Direct (Zepbound vial 5mg)Manufacturer directZepbound vial$499$499Intake screen
NovoCare (Wegovy Savings Card)Commercial insurance required for $0 first monthManufacturer directWegovy 2.4mg$0$225Source
GoodRx (Ozempic)Pharmacy couponOzempic 1mg$950$950Source
SingleCare (Ozempic)Pharmacy couponOzempic 1mg$920$920Source
Cost Plus Drugs (Ozempic)Limited US stock, intermittentPharmacy couponOzempic 1mg$287$287Source
CareCard (Wegovy)Pharmacy couponWegovy 2.4mg$1198$1198Intake screen

What the spread reveals

The first finding: the cash market has fully fragmented in 2026. Three years ago the choice was brand-name pen at list price (~$1,300/mo) or nothing. Today there are at least four distinct supply chains, each with its own regulatory status, quality assurance posture, and target patient profile.

The second finding: compounded semaglutide from licensed 503A pharmacies has settled around $199-297/mo as competition intensified through 2025-2026. Below $199/mo, walk away β€” the provider either uses unverified API or operates outside US pharmacy licensure.

The third finding: Eli Lilly's direct-to-patient Zepbound vial program (launched mid-2024) is the most disruptive single move in the brand-name cash market. $349/mo for the 2.5 mg starter vial is below every brand-name telehealth provider listed here.

The fourth finding: pharmacy coupon platforms (GoodRx, SingleCare, CareCard) discount the brand-name retail price by 10-25%, but they don't approach the compounded or Lilly Direct floor. Cost Plus Drugs sells brand-name Ozempic at $287/mo when in stock β€” closest competitor to the manufacturer-direct floor.

Methodology

Prices captured 2026-05-25 through 2026-05-31 from each provider's public rate card or intake screen. Compounded providers' prices fluctuate with API supply and were snapshot at the median of the past 30 days. Manufacturer-direct prices are FDA-approved label cash prices. Pharmacy coupon prices are the median for ZIP 10001 (New York City) on the platform's lookup tool.

Refresh cadence: quarterly. Next update: 2026-09-01.

Where to start

Compounded 503A providers in the table above

Direct links to the providers whose cash prices we surveyed. We are not yet an affiliate partner with most.

Editorial selection. "Direct" links go to the company’s homepage β€” we are not yet an affiliate partner with them and earn no commission on those signups. "Affiliate" links route through our /go redirect with commission tracking.

Pair this with

Common questions

Why is the GLP-1 cash-price spread so wide?

Three distinct supply chains exist: compounded 503A (cheapest, $149-449/mo), manufacturer-direct vials (Lilly Direct $349-499/mo), and brand-name pen via telehealth ($499-1,349/mo). Each has different regulatory status, quality assurance, and insurance pathway. Spread comes from supply-chain choice, not just markup.

Which is the cheapest legal GLP-1 in 2026?

Compounded semaglutide from licensed 503A pharmacies starts at $199/mo (Push Health) β€” legal when prescribed for patient-specific need. Hims oral Wegovy at $149/mo is the cheapest brand-name path, but only on the introductory tier.

How often do these prices change?

We refresh this dataset quarterly from each provider's public rate card or intake screen. Compounded prices drop fastest (competitive race-to-bottom in 2026). Brand-name prices are sticky β€” Novo Nordisk and Eli Lilly hold list prices; movement comes from savings cards and direct-to-patient programs.

Is compounded GLP-1 the same as brand-name?

Same active molecule when sourced from USP-grade suppliers; different in FDA oversight (compounded is not FDA-approved as a finished product), inactive ingredients, and sterility-process variability between pharmacies. See our compounded-vs-brand pillar for the full safety + legality picture.

Methodology + raw data licensed CC-BY 4.0. We encourage other researchers + journalists to cite this dataset; attribution to Health Portal with a link back is the only requirement.