Cash-pay GLP-1 pricing varies more than any other drug class in 2026. Brand-name cash list prices: Wegovy ~$1,199/month, Zepbound ~$1,059/month, Ozempic ~$968/month, Mounjaro ~$1,135/month.
Manufacturer savings cards substantially reduce cost for eligible commercially-insured patients: Novo Nordisk's WegovyCare drops to $499/month with insurance; LillyDirect self-pay program lowers Zepbound to ~$499/month for compounded-to-brand switchers.
Compounded semaglutide remains the cheapest path — $99-$249/month through telehealth providers — but access has tightened since the FDA declared the shortage resolved in 2025.
Use the savings calculator to compare 12-month projected costs across providers, factoring in consult fees, shipping, and savings cards.