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Medication comparison

Ozempic vs Wegovy

Medically reviewed by Dr. Jane Novak, MD, MPH 8 min read Fact checked Editorial integrityUpdated Jun 5, 2026

Ozempic and Wegovy are both GLP-1 receptor agonist medications used for Type 2 diabetes and Chronic weight management. The table below compares FDA-approved indications, dosing, weight-loss outcomes, side effects, contraindications, and current pricing — all sourced from the manufacturer prescribing information.

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This is general drug information, not medical advice. Talk to a licensed clinician before starting, stopping, or switching medication.

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Drug A

Ozempic

semaglutide

GLP-1 receptor agonist

Novo Nordisk

See full overview

Drug B

Wegovy

semaglutide

GLP-1 receptor agonist

Novo Nordisk

See full overview

Overview

PropertyOzempicWegovy
Generic namesemaglutidesemaglutide
Drug classGLP-1 receptor agonistGLP-1 receptor agonist
ManufacturerNovo NordiskNovo Nordisk
Brand namesOzempicWegovy

Approved uses

PropertyOzempicWegovy
Approved indicationsType 2 diabetesChronic weight management

Dosing

PropertyOzempicWegovy
Typical dosingTitrate to 2.0 mg (weekly SC injection)Titrate to 2.4 mg (weekly SC injection)

Side effects & warnings

PropertyOzempicWegovy
Top side effectsNausea (20.3%), Vomiting (9.2%), Diarrhea (8.5%)Nausea (44.2%), Diarrhea (31.5%), Vomiting (24.8%)
Contraindications——
Boxed warningYesYes

Special populations

PropertyOzempicWegovy
PregnancyC — Discontinue at least 2 months before a planned pregnancy.C — Discontinue at least 2 months before a planned pregnancy.

Storage

PropertyOzempicWegovy
StorageRefrigerate before first use. After first use, room temperature up to 56 days. Protect from light.Refrigerate before first use. After first use, room temperature up to 28 days.

Cost

PropertyOzempicWegovy
Avg monthly cost$935.77$1349.02

FDA boxed warning

Ozempic: Risk of thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Wegovy: Risk of thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Already on Ozempic and considering Wegovy?

Same drug (semaglutide), different FDA indication — for patients who want weight-loss coverage.

Read the switching guide

Frequently asked

What is the difference between Ozempic and Wegovy?

Ozempic is semaglutide (GLP-1 receptor agonist) and Wegovy is semaglutide (GLP-1 receptor agonist). Both contain the same active ingredient, dosed differently for different FDA-approved indications.

Is Ozempic or Wegovy more effective for weight loss?

Ozempic and Wegovy share the same active ingredient (semaglutide). Average weight loss outcomes track the FDA-approved dose for each brand: STEP 1 reported 14.9% mean weight loss on the higher chronic-weight-management dose vs roughly half that on the lower diabetes-dose. The differentiator is dosing and indication, not molecule potency.

Can I switch between Ozempic and Wegovy?

Yes — see our directional switching guide at /switching/ozempic-to-wegovy for FDA-label dose conversion and what to expect during the transition.

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