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Medication comparison

Wegovy vs Ozempic

Medically reviewed by Dr. Jane Novak, MD, MPH 8 min read Fact checked Editorial integrityUpdated Jun 5, 2026

Wegovy and Ozempic are both GLP-1 receptor agonist medications used for Chronic weight management and Type 2 diabetes. The table below compares FDA-approved indications, dosing, weight-loss outcomes, side effects, contraindications, and current pricing — all sourced from the manufacturer prescribing information.

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This is general drug information, not medical advice. Talk to a licensed clinician before starting, stopping, or switching medication.

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Drug A

Wegovy

semaglutide

GLP-1 receptor agonist

Novo Nordisk

See full overview

Drug B

Ozempic

semaglutide

GLP-1 receptor agonist

Novo Nordisk

See full overview

Overview

PropertyWegovyOzempic
Generic namesemaglutidesemaglutide
Drug classGLP-1 receptor agonistGLP-1 receptor agonist
ManufacturerNovo NordiskNovo Nordisk
Brand namesWegovyOzempic

Approved uses

PropertyWegovyOzempic
Approved indicationsChronic weight managementType 2 diabetes

Dosing

PropertyWegovyOzempic
Typical dosingTitrate to 2.4 mg (weekly SC injection)Titrate to 2.0 mg (weekly SC injection)

Side effects & warnings

PropertyWegovyOzempic
Top side effectsNausea (44.2%), Diarrhea (31.5%), Vomiting (24.8%)Nausea (20.3%), Vomiting (9.2%), Diarrhea (8.5%)
Contraindications——
Boxed warningYesYes

Special populations

PropertyWegovyOzempic
PregnancyC — Discontinue at least 2 months before a planned pregnancy.C — Discontinue at least 2 months before a planned pregnancy.

Storage

PropertyWegovyOzempic
StorageRefrigerate before first use. After first use, room temperature up to 28 days.Refrigerate before first use. After first use, room temperature up to 56 days. Protect from light.

Cost

PropertyWegovyOzempic
Avg monthly cost$1349.02$935.77

FDA boxed warning

Wegovy: Risk of thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Ozempic: Risk of thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).

Already on Wegovy and considering Ozempic?

Same drug, different label — usually a cost / insurance driver, not a clinical one.

Read the switching guide

Frequently asked

What is the difference between Wegovy and Ozempic?

Wegovy is semaglutide (GLP-1 receptor agonist) and Ozempic is semaglutide (GLP-1 receptor agonist). Both contain the same active ingredient, dosed differently for different FDA-approved indications.

Is Wegovy or Ozempic more effective for weight loss?

Wegovy and Ozempic share the same active ingredient (semaglutide). Average weight loss outcomes track the FDA-approved dose for each brand: STEP 1 reported 14.9% mean weight loss on the higher chronic-weight-management dose vs roughly half that on the lower diabetes-dose. The differentiator is dosing and indication, not molecule potency.

Can I switch between Wegovy and Ozempic?

Yes — see our directional switching guide at /switching/wegovy-to-ozempic for FDA-label dose conversion and what to expect during the transition.

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