Trial-sourced incidence data

Ozempic side effects

Ozempic (semaglutide) has 5 documented side effects from peer-reviewed Phase 3 trial data. Click any effect for a patient-facing deep dive with management guidance.

• Nausea

  moderate·20.3% of trial patients·gastrointestinal

• Vomiting

  moderate·9.2% of trial patients·gastrointestinal

• Diarrhea

  moderate·8.5% of trial patients·gastrointestinal

• Constipation

  mild·6.5% of trial patients·gastrointestinal

• Headache

  mild·5.7% of trial patients·nervous

Incidence rates from peer-reviewed pivotal-trial publications and FDA prescribing information. Individual experience varies — discuss any new symptoms with your prescriber. Medically reviewed by Jane Novak, MD, MPH.