Ozempic side effect
Ozempic Constipation: causes, relief, and when to call a doctor
Constipation is reported by 15β25% of patients on GLP-1s. Slowed gastric emptying plus reduced food intake means less bulk reaching the colon β so stools become harder and less frequent.
In trial β Ozempic
23.4%
In trial β placebo
9.5%
Severity
mild
Source: STEP-1 (Wilding et al., NEJM 2021)