Zepbound (tirzepatide) runs about $1086/month at retail without insurance. With coverage the copay is around $25, and the lowest cash-pay path we track starts near $349/month — up to 68% off retail.
What Zepbound costs in 2026
From $349/mo via telehealth68% off retail
Average retail in the US: $1086/month. We compare 4 pricing paths below so you can see exactly where the savings come from.
| Pricing path | Monthly cost |
|---|---|
Retail pharmacy Cash, no insurance, no coupon | $1,086 |
GoodRx coupon Same pharmacy, public coupon | $1,059 |
Commercial insurance Typical copay (median) | $25 |
Ro Cheapest editorially-vetted path | $349 68% off retail |
Prices refreshed 2026-05-24. Retail = pharmacy cash price; coupon = GoodRx-style discount; telehealth = lowest cash-pay program we list.
12-month cost tracker
Average US retail pharmacy price, per 28-day supply. Hand-curated; updated monthly.
Cash price held flat over the past year
Prices reflect average list at major US pharmacies (CVS, Walgreens, Walmart). Your actual cost depends on insurance, pharmacy choice, and savings-card eligibility.
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Without insurance, Zepbound runs about $1086/month at retail pharmacy. A GoodRx-style coupon brings that to roughly $1059. The lowest cash-pay path we track is a telehealth program from about $349/month (Ro).
With commercial insurance that covers Zepbound, the typical copay is around $25/month, though many plans exclude weight-loss use and require prior authorization. Check your specific plan with our insurance checker.
In order of typical cost: manufacturer savings card if you have commercial insurance, then a cash-pay telehealth program (from ~$349/mo), then a GoodRx coupon at retail ($1059), then full retail ($1086). Patient-assistance programs may cover it entirely if you are income-qualified.