Zepbound (tirzepatide) runs about $1086/month at retail without insurance. With coverage the copay is around $25, and the lowest cash-pay path we track starts near $349/month — up to 68% off retail.
What Zepbound costs in 2026
From $349/mo via telehealth68% off retail
Average retail in the US: $1086/month. We compare 4 pricing paths below so you can see exactly where the savings come from.
| Pricing path | Monthly cost |
|---|---|
Retail pharmacy Cash, no insurance, no coupon | $1,086 |
GoodRx coupon Same pharmacy, public coupon |
12-month cost tracker
Average US retail pharmacy price, per 28-day supply. Hand-curated; updated monthly.
Cash price held flat over the past year
Standard 2026 formulary status across the five largest US payers. Verify against your plan — self-funded employer plans can override the payer formulary with a weight-loss exclusion.
| Payer | Tier / status | PA required | Typical copay |
|---|---|---|---|
| UnitedHealthcare (OptumRx) | Tier 3 or 4 | Yes · 7-14 d | $25-100/mo |
| Aetna (CVS Caremark) | Tier 3 | Yes · step-therapy common | $25-80/mo |
| Cigna (Express Scripts) | Tier 3 | Yes · comorbidity req. | $25-90/mo |
| BCBS (varies by state) | Tier 3 | Yes · state formulary | $25-100/mo |
| Kaiser Permanente | Formulary + network | Yes · in-Kaiser MD | $5-50/mo |
| Medicare Part D (T2D only) | On-label diabetes | Weight-loss excluded by statute | $50-100/mo (T2D) · $0 wt-loss |
| Medicaid (state-by-state) |
We earn a commission if you sign up through our links, at no cost to you; rankings are editorial. How we rank.
Without insurance, Zepbound runs about $1086/month at retail pharmacy. A GoodRx-style coupon brings that to roughly $1059. The lowest cash-pay path we track is a telehealth program from about $349/month (Ro).
With commercial insurance that covers Zepbound, the typical copay is around $25/month, though many plans exclude weight-loss use and require prior authorization. Check your specific plan with our insurance checker.
In order of typical cost: manufacturer savings card if you have commercial insurance, then a cash-pay telehealth program (from ~$349/mo), then a GoodRx coupon at retail ($1059), then full retail ($1086). Patient-assistance programs may cover it entirely if you are income-qualified.
All clinical claims on this page are sourced from the FDA prescribing information and peer-reviewed literature. Verify the most current label before clinical decisions.
Commercial insurance Typical copay (median) | $25 |
Ro Cheapest editorially-vetted path | $349 68% off retail |
Prices refreshed 2026-05-24. Retail = pharmacy cash price; coupon = GoodRx-style discount; telehealth = lowest cash-pay program we list.
Prices reflect average list at major US pharmacies (CVS, Walgreens, Walmart). Your actual cost depends on insurance, pharmacy choice, and savings-card eligibility.
| Varies |
| Yes · PA + BMI + comorbidity |
| $0-8/mo where covered |
| Self-funded employer (ERISA) | Plan-specific | ≈30% carry weight-loss exclusion | Varies |
|---|
Sourced from public payer PDLs (2026 formulary year). Employer self-funded plans (ERISA) override the payer formulary — check with your HR benefits team or the number on the back of your card.
Price sources: retail and coupon figures from GoodRx (opens in a new tab) (refreshed monthly) and published manufacturer savings programs. Insurance copays vary by plan and formulary tier — confirm current pricing with your pharmacy and insurer.