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HomeQ&ADoes Ozempic cause hair loss?

Evidence-graded answer

Does Ozempic cause hair loss?

BReviewed by Jane Novak, MD, MPHΒ· Updated 2026-05-30

Not directly. Hair shedding (telogen effluvium) is reported by some patients ~3 months into rapid weight loss β€” typical of any rapid-weight-loss state, not unique to GLP-1.

Telogen effluvium is hair follicles shifting prematurely from growth to shedding phase, usually triggered by physiologic stress including rapid weight loss, surgery, or major illness.

STEP-1 trial (semaglutide 2.4 mg) reported alopecia in 3% of treated patients vs 1% placebo β€” a small absolute increase consistent with rapid-weight-loss hair shedding rather than a drug-specific effect.

Most patients see hair regrowth 6-12 months after weight stabilizes. Adequate protein intake (1.2-1.6 g/kg ideal body weight) and iron labs are reasonable next steps.

Source: STEP-1 NEJM 2021, NEJM (opens in a new tab)

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Does Ozempic cause hair loss?