HomeDiariesWegovy Β· Month 1

Wegovy Diary: a 6-month chronicle

Wegovy Diary Month 1: the first injection, peak nausea, food noise quiet

A composite first-month chronicle of starting Wegovy at 0.25 mg. What injection day actually feels like, when the food noise drops, and what hit me at week 3 that nobody warned me about.

By Marina S. Β· Composite patient persona, reviewed by MDReviewed by Jane Novak, MD, MPHPublished 2026-06-01

Week 1. The starter dose pen arrives on Tuesday. I inject Sunday evening at 8pm β€” picked the time deliberately so any side effects peak during the work-free hours. The injection itself is anticlimactic: a brief sting, two clicks, and a small bead of plasma at the site. I rotate to my left abdomen, two inches from my navel.

Week 2. The nausea everyone warned me about lands at hour 36. It's not the food-poisoning kind β€” more like the second-trimester pregnancy kind. Greasy food turns my stomach the moment I think about it. I switch to plain yogurt, crackers, plain rice for two days and the wave passes.

Week 3. The thing nobody warned me about: the food noise stops. I've spent thirty years with a low-level background hum in my head β€” what's for dinner, is there ice cream left, can I justify the chips. By Tuesday morning of week 3 the hum is gone. I sit down to lunch, eat half my sandwich, and notice I'm not interested in the other half. It feels almost like a personality change. I'm not exaggerating when I say it took two more weeks to get used to the quiet.

Week 4. Dose step-up to 0.5 mg this Sunday. Side-effect window resets briefly β€” same playbook as weeks 1-2: hydration, smaller meals, fiber. By Friday I am back to baseline. Scale shows down 7 lb at the end of week 4, mostly water + reduced volume. Real fat loss starts next month.

Quantified diary data. Week 1: 0.25 mg dose, weight 224 lb (101.6 kg). Week 4: 0.5 mg dose, weight 217 lb (98.4 kg). Total month 1: βˆ’7 lb (βˆ’3.2 kg). Side effects: mild nausea (peaked weeks 2-3), one episode of reflux at week 3. No vomiting, no constipation past two days.

Continue Β· Month 2

Wegovy Diary Month 2: the boring middle, first restaurant test, the scale catches up

See the full Wegovy drug profile
People also ask

Common questions readers ask

Does Ozempic cause hair loss?
Not directly. Hair shedding (telogen effluvium) is reported by some patients ~3 months into rapid weight loss β€” typical of any rapid-weight-loss state, not unique to GLP-1.
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Can you drink alcohol on Wegovy?
No hard contraindication, but alcohol tolerance often drops sharply on GLP-1. Many patients also report reduced desire for alcohol β€” likely a secondary effect of GLP-1 on the brain reward system.
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Do I need to exercise on Wegovy?
Yes β€” resistance training specifically. Without it, 25-40% of weight lost on GLP-1 comes from lean muscle. Cardio is a bonus; resistance is the non-negotiable.
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Can vegetarians or vegans take GLP-1?
Yes. Modern GLP-1 medications are produced via yeast fermentation, not animal sources. The pen device and packaging contain no animal-derived materials in current FDA-approved products.
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