Week 1. 2.5 mg starter dose, Sunday evening, abdomen. The injection is a single click — Zepbound pens are different from Wegovy's two-click design. Small sting, no bead. The pen design feels engineered for a more confident user; that's a minor but real UX win.
Week 2. The appetite change is different from what I read about Wegovy. With Zepbound, I don't lose interest in food — I lose interest in volume. I want a normal dinner. I'm satisfied after half a normal dinner. That's the distinction.
Week 3. Mild nausea peaks midweek. Resolves by Sunday. I switch dinner protein to baked salmon + rice + roasted vegetables and the GI calms down within three days.
Week 4. Dose step-up to 5.0 mg. This is the first therapeutic dose. The effect compounds — I notice I am not snacking between meals at all. Quantified data: started 218 lb, finished month 1 at 211 lb. −7 lb in 4 weeks.
Quantified diary data. Week 1: 2.5 mg, 218 lb. Week 4: 5 mg, 211 lb. Month 1: −7 lb. Mild nausea (peaked week 3), no vomiting, mild constipation that resolved with fiber.