Medications A–Z
5 entries — 2 medications, 2 conditions, 1 term.
Obesity is a chronic, relapsing disease defined by excess body fat that increases health risk. The medical threshold is BMI ≥30, or ≥27 with a weight-related comorbidity. GLP-1 medications Wegovy and Zepbound are FDA-approved for chronic weight management and produce 14–21% mean weight loss in clinical trials.
Obstructive sleep apnea (OSA) is a chronic condition in which breathing repeatedly stops and starts during sleep due to airway collapse. In December 2024 the FDA expanded Zepbound's indications to include moderate-to-severe OSA in adults with obesity — the first weight-loss drug approved for the condition.
Prescribing an FDA-approved drug for a condition it is not approved for. Using Ozempic for weight loss is off-label since Ozempic is approved only for type 2 diabetes; insurance typically refuses coverage in this scenario.
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