Trial-sourced incidence data

Ozempic side effects

Ozempic (semaglutide) has 6 documented side effects from peer-reviewed Phase 3 trial data. Click any effect for a patient-facing deep dive with management guidance.

• Nausea

  moderate·44.2% of trial patients·gastrointestinal

• Diarrhea

  moderate·31.5% of trial patients·gastrointestinal

• Vomiting

  moderate·24.8% of trial patients·gastrointestinal

• Constipation

  mild·23.4% of trial patients·gastrointestinal

• Headache

  mild·14.6% of trial patients·nervous

• Fatigue

  mild·11% of trial patients·general

Incidence rates from peer-reviewed pivotal-trial publications and FDA prescribing information. Individual experience varies — discuss any new symptoms with your prescriber. Medically reviewed by Jane Novak, MD, MPH.